会员登录|免费注册|忘记密码|管理入口 返回主站||保存桌面
健康大数据时代:英国生物样本库如何改变医学研究
2025-12-08IP属地 湖北0


其次,UK Biobank的数据具有持续性,这为研究带来了独特的优势。以在线问卷数据为例,自2011年起,UK Biobank逐步扩展问卷内容:最初是饮食习惯,2014年加入了认知功能的内容,2015年增加了职业史以探讨工作环境与健康的关联,2016年又开始关注心理健康问题。到2023年,问卷进一步扩展,涵盖了睡眠质量、社交互动、注意力、想象力和记忆等内容。2024年,UK Biobank新增了慢性疼痛的问卷,以深入了解慢性疼痛的类型、持续时间和严重程度。在志愿者加入后,数据的收集并非一次性完成。UK Biobank会不断构建新的研究内容,持续更新数据。这项前瞻性流行病学研究自2006年启动,预计将持续到2036年,对参与者的健康和医疗状况进行长期跟踪。数据的连续性带来了显著的优势,不仅支持长期的跟踪和趋势分析,帮助研究人员观察健康状况和生活方式随时间的变化,还能够揭示潜在的因果关系。这种持续的数据收集提高了数据的完整性和可靠性,支持深入的多变量分析,揭示不同因素之间的相互作用。


Secondly, UK Biobank’s data is continuous, which offers unique advantages for research. Taking the online questionnaire data as an example: since 2011, UK Biobank has gradually expanded its questionnaire content. It began with dietary habits, then added cognitive function in 2014, occupational history in 2015 to explore the links between work environment and health, and mental health issues in 2016. By 2023, the questionnaire had expanded further to include sleep quality, social interactions, attention, visualization, and memory. In 2024, UK Biobank introduced a new questionnaire on chronic pain to deepen understanding of its types, duration, and severity. Data collection for volunteers is not a one-time process; UK Biobank continuously builds on new research areas and updates its data. This prospective epidemiological study began in 2006 and is expected to continue until 2036, providing long-term tracking of participants’ health and medical conditions. The continuity of data offers significant advantages, such as supporting long-term tracking and trend analysis, helping researchers observe how health conditions and lifestyles change over time, and identifying causal relationships. This ongoing data collection enhances data completeness and reliability, enabling in-depth multivariable analysis and uncovering interactions between different factors.